Aggregating it by state doesn't make a ton of sense when housing dominates the budget of most people. It's really more about MSAs.
As far as pulling itself out of the basement, we have several decent places to live between "south Memphis", Tupelo, Hattiesburg, the Coast, and I guess Madison. If we had one vibrant city to keep people from leaving the state, you'd probably see a lot more people move to those places after getting tired of a more urban setting. It's a little bit harder to come from Charlotte, Denver, Atlanta, DFW, Houston, etc. back to small time Mississippi because that usually involves losing the benefit of a lot of your professional network.
Not having a vibrant city is a killer in today's economy. Really need to hope that the Coast takes off because I think the coast and South Memphis are the only places with a hcance, and I think South Memphis will always be a quasi bedroom community unless Memphis gets so bad that lots of business starts decamping to North Mississippi. Not sure that would turn any of that into a desirable city though; I think it'd still mostly feel like suburbs.