2025 NCAA Tournament: Updated national title odds for March Madness following Selection Sunday

March Madness is officially here as the 2025 NCAA Tournament field was announced Sunday on CBS, and the first look at the betting odds is here. With the “First Four” set to begin on Tuesday, FanDuel has updated its odds for the national champion.

The Round of 64 will then follow on Thursday as we wait to find out which Cinderella will capture our hearts this year. But as you get ready to pick your bracket Sunday evening ahead of all the action, these odds can serve as a good reference point when picking your champ.

Duke Blue Devils (+310)

Led by freshman phenom Cooper Flagg, the Blue Devils enter as the favorite to win the 2025 national championship. Flagg is the projected No. 1 overall this pick after this season and has looked the part to average 18.9 points, 7.5 rebounds and 4.1 assists.

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Duke showed it is more than just Flagg on Saturday to defeat Louisville and win the ACC Tournament, claiming an automatic bid. Tyrese Proctor stepped up to nail a career-high six 3-pointers, while Kon Knueppel chipped in 18 points and eight rebounds.

Florida Gators (+400)

The Gators are fresh off of an SEC Tournament title win on Sunday against Tennessee. It marked the first time they had won the conference tournament since 2014, a year in which it would go on to advance to the Final Four.

Florida’s biggest advantage is its size, as it starts a pair of 6-11 big men in Alex Condon and Rueben Chinyelu to rank third in the country in rebounds per game (42.1). Guards Walter Clayton Jr. and Alijah Martin hold things down on the perimeter to rank first and second on the team in scoring, respectively.

Auburn Tigers (+500)

Auburn earned the No. 1 overall seed for the first time in school history after a dominant performance that saw them finish the regular season 28-5. Now it will look to back that up as it aims for its second Final Four appearance and first title in program history.

The Tigers are a veteran-laden squad and will hope that experience gives it even more of an advantage against its opponents. Big man Johni Broome is the team leader with 18.9 points, 10.6 rebounds and 2.3 blocks per game, the latter two of which led the SEC.

Houston Cougars (+700)

Despite 22 total NCAA Tournament appearances and two Final Fours, coach Kelvin Sampson has never won a national title in his career. FanDuel believes he has a solid shot to change that this time around as it gives Houston the fourth-best championship odds.

This is the third straight season that the Cougars have earned a No. 1 seed, as they find themselves as the top seed in the Midwest Region. Houston lost in the Sweet Sixteen each of the past two seasons and will hope the saying “defense wins championships rings true” as it enters the tournament as the nation’s No. 2 defense according to KenPom.

Alabama Crimson Tide (+1900)

The Crimson Tide are the third SEC team ranked inside the top five of the odds to win the NCAA Tournament. They advanced to the Final Four last season and have a chance to not only make it back, but finish things off by hoisting a trophy at the end.

Mark Sears returns from that team and leads Alabama with 18.7 points and 4.9 assists this season. He and Grant Nelson give the Crimson Tide a pair of starters who know what it’s like to make a deep tournament run, and they’ll aim for just that.

Tennessee Volunteers (+2100)

Tennessee fell just short in the SEC Tournament title game against Florida, but will look to bounce back with a deep tournament run. The Vols are coming off of an Elite Eight appearance a year ago and have veteran point guard Zakai Zeigler, who leads the SEC with 7.3 assists per game.

Dalton Knecht might be gone to the NBA, but North Florida transfer Chaz Lanier has stepped in to fill the leading scoring role with 17.9 points per game on 40.4% shooting from 3-point range. Tennessee earned a No. 2 seed and will have to get past Houston to reach the Final Four.

Texas Tech Red Raiders (+2400)

The Red Raiders fell in the first round last season in the inaugural year for coach Grant McCasland. But after finishing 25-8 this season and earned a No. 3 seed, they are ready to get their revenge.

Texas Tech actually has higher odds to win the title than the No. 2 seed in its region, which is St. John’s. They’ve certainly got the star power to do so, with JT Toppin leading the way and averaging 18.1 points and 9.2 rebounds per game.

Michigan State Spartans (+3000)

The Spartans find themselves in a familiar position, having made the NCAA Tournament for 27 consecutive seasons, the longest active streak in the NCAA. They’ve won one championship under coach Tom Izzo and made it to the Final Four eight times, most recently in 2019.

This year’s squad enters as a No. 2 seed in South Region, where it could face a potential matchup with top-seeded Auburn in the Elite Eight. Michigan State truly gets things done with a balanced attack and sound defense, with no player on its team averaging over 13 points per game.

Iowa State Cyclones (+3000)

Iowa State was dealt a tough blow, as it was revealed that Keshon Gilbert will miss the NCAA Tournament due to a groin injury. Gilbert has been out for the previous seven games as the Cyclones went 3-4 during that span.

That certainly doesn’t bode well for a long run, but FanDuel still ranks ISU inside the top 10 for national title odds. It will need Curtis Jones, who leads the team with 17.1 points per game, to step even more in his absence.

St. John’s Red Storm (+3200)

St. John’s hasn’t had a season like this in a long time, as it reached 30 wins for the first time since 1985-86. The Red Storm reached their second Final Four in school history that season but are still in search of their first national title.

St. John’s earned a No. 2 seed, which its highest since 2000, and is making its first NCAA Tournament appearance since 2019. They’ve also got an experienced coach in Rick Pitino and a veteran group of starts, two ingredients for a potential deep run.

More NCAA Tournament national championship odds

• Gonzaga Bulldogs (+3600)
• Arizona Wildcats (+3800)
• Illinois Fighting Illini (+5000)
• Kentucky Wildcats (+5000)
• Maryland Terrapins (+5500)
• Wisconsin Badgers (+5500)
• Missouri Tigers (+6500)
• Purdue Boilermakers (+6500)
• Kansas Jayhawks (+6500)
• Texas A&M Aggies (+8000)
• Clemson Tigers (+10000)
• BYU Cougars (+10000)

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