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Last Minute Bets: Week 10 odds for College Football's biggest games

ns_headshot_2024-clearby:Nick Schultz11/02/24

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Last Minute Bets: Week 10 odds for College Football's biggest games
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It’s officially November, which means games are going to get that much more important across college football. Some notable matchups await in Week 10, and FanDuel has the Last Minute Bets for the biggest games on the slate.

A key ranked showdown awaits in Happy Valley as No. 3 Penn State and No. 4 Ohio State square off in the biggest game of Week 10. The game has not only has major Big Ten implications, but will also have an impact on the College Football Playoff race ahead of Tuesday’s first rankings reveal.

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Of course, there’s also the World’s Largest Outdoor Cocktail Party rivalry between Florida and Georgia in Jacksonville. It’s just one of the marquee matchups on the Week 10 schedule. Here are the Last Minute Bets for the biggest games, according to FanDuel.

1. Oregon at Michigan

Time: 3:30 p.m. ET
Channel: CBS

Oregon remained atop the AP Top 25 rankings this week after a resounding victory over Illinois at Autzen Stadium a week ago. The Ducks bring an undefeated record into a matchup at Michigan, and they enter as double-digit favorites, according to FanDuel.

FanDuel point spread: Oregon -14.5
FanDuel over/under: 44.5

2. Georgia vs. Florida

Billy Napier, Kirby Smart
Photo by Doug Engle / USA TODAY Sports

Time: 3:30 p.m. ET
Channel: ABC

The World’s Largest Outdoor Cocktail Party returns to Jacksonville this week in what could be one of the most intriguing games of the year. There are plenty of storylines as Georgia takes on Florida, including what the matchup could mean for Billy Napier’s future in Gainesville.

FanDuel point spread: Georgia -14.5
FanDuel over/under: 51.5

3. Penn State vs. 4. Ohio State

Time: Noon ET
Channel: FOX

Penn State and Ohio State will square off in yet another Top-5 matchup this season. Both teams are looking to keep their College Football Playoff hopes alive in a crowded Big Ten, and all eyes will be on Happy Valley. The Buckeyes enter as 3.5-point road favorites, according to FanDuel.

FanDuel point spread: Ohio State -3.5
FanDuel over/under: 47.5

5. Miami vs. Duke

Time: Noon ET
Channel: ABC

For the first time since his departure, Manny Diaz makes his return to Miami – this time, as Duke head coach. The Blue Devils will look to bounce back from an overtime loss to SMU last week, but will face a tall task against an undefeated Hurricanes team that doesn’t show many signs of slowing down.

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FanDuel point spread: Miami -20.5
FanDuel over/under: 54.5

7. Tennessee vs. Kentucky

Tennessee HC Josh Heupel
(Saul Young | News Sentinel | USA TODAY NETWORK)

Time: 7:45 p.m. ET
Channel: SEC Network

Tennessee had an extra week to enjoy its rivalry win over Alabama, but it’s back to business this week as the Vols welcome Kentucky to Rocky Top. They’ve bounced back well from a loss to Arkansas and enter Saturday’s game as 17.5-point favorites, according to FanDuel.

FanDuel point spread: Tennessee -17.5
FanDuel over/under: 45.5

10. Texas A&M at South Carolina

Time: 7:30 p.m. ET
Channel: ABC

Texas A&M hasn’t lost since falling to Notre Dame in Week 1, and Mike Elko’s group is now in the Top 10 after defeating LSU in thrilling fashion last time out. The Aggies will look to keep things rolling as they hit the road for another primetime showdown, this time at a hostile environment in South Carolina.

FanDuel point spread: Texas A&M -2.5
FanDuel over/under: 43.5

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More Top-25 lines for Week 10

11. Clemson (-10.5) vs. Louisville – over/under: 61.5
11. Iowa State (-13.5) vs. Texas Tech – over/under: 56.5
13. Indiana (-7.5) vs. Michigan State – over/under: 53.5
17. Kansas State (-13.5) at Houston – over/under: 45.5
18. Pitt at 20. SMU (-7.5) – over/under: 57.5
19. Ole Miss (-7.5) at Arkansas – over/under: 54.5
21. Army (-21.5) vs. Air Force – over/under: 41.5
24. Illinois (-3.5) vs. Minnesota – over/under: 45.5

CLICK HERE to get in your Last Minute Bets with FanDuel!

November is here, meaning there are just a few weeks left in the regular season. Conference races are going to heat up, and the race to the College Football Playoff is entering the final stretch.