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National Championship Odds: Betting favorites see shakeup after Week 7 of college football

IMG_6598by: Nick Kosko10/13/25nickkosko59
National Championship Odds: Betting favorites see shakeup after Week 7 of college football
Adam Cairns | Columbus Dispatch | USA TODAY NETWORK via Imagn Images

The latest national championship odds are here and they saw a shakeup following Week 7 of college football. All odds are courtesy of BetMGM.

Indiana made a giant statement by beating Oregon on the road and is one of the top tier favorites to win it all. Imagine writing that sentence just two years ago!

Without further ado, let’s dive into the latest national championship odds. We’ll start with the favorite.

Ohio State (+350)

Ohio State is the favorite for the national championship once again as the Buckeyes are still undefeated. They lead the Big Ten and just beat Illinois on the road, handedly.

It helps that you have a solid QB in Julian Sayin, a dominant defense and two superstars in WR Jeremiah Smith and DB Caleb Downs. Ryan Day and crew are the pick until further notice, if you’re picking the shortest odds of course.

Alabama (+600)

Alabama coach Kalen DeBoer
Alabama coach Kalen DeBoer (Jay Biggerstaff / Imagn Images)

Alabama won its fifth straight game, beating Missouri this weekend. Ty Simpson is playing at a high level and the defense is hitting its stride.

With the latest movement, the Crimson Tide are one of the favorites to win the national championship. Kalen DeBoer could get back to the big game for the second time in three years!

Miami (+800)

Miami had the week off but still are one of the top favorites for the national championship later this season. Carson Beck is a Heisman contender and everything’s clicking right now for the Hurricanes.

Mario Cristobal and company take on Louisville Friday night as the Cardinals come to Coral Gables. They’ll be favorites to get to 6-0 on the year. 

Indiana (+900)

It’s amazing to see what Indiana has done in a year and a half. Curt Cignetti proved last year’s playoff team was no fluke.

This is a true national championship contender right now. The Hoosiers are 6-0, ranked No. 3 in the country, just beat Oregon and probably have their eyes set on a Big Ten title at this point.

Georgia (+1,000)

Georgia head coach Kirby Smart during Georgia’s game against Alabama on Dooley Field at Sanford Stadium in Athens, Ga., on Saturday, Sept. 27, 2025.
(Tony Walsh/UGAAA)

Georgia beat Auburn on the road to win their second straight game after a loss to Alabama. Despite that loss, the Bulldogs are in the national championship picture.

Kirby Smart and crew will host Ole Miss in a top 10 matchup this weekend. Expect that to be the game of the weekend.

Oregon (+1,000)

The Ducks are by no means out of the national championship picture by losing to Indiana at home. It was a bit surprising, sure, but this was considered one of the best teams, if not the best, just last week.

Dan Lanning and crew have a get-right game in front of them with Rutgers on the road. A win in conference play cross country could get them back in the swing of things and maybe a rematch with Indiana down the road.

Texas A&M (+1,400)

The Aggies just keep winning and it seems like other SEC and Big Ten teams take away the spotlight. Maybe Mike Elko is just fine with that.

But with their current national championship odds, you can’t hide this team forever. Texas A&M heads to Arkansas this weekend before hitting the road to play LSU and Missouri over the course of a three week span. That’ll be must-see TV.

Texas (+1,600)

Steve Sarkisian, Texas
© Kevin Jairaj-Imagn Images

Texas is back in it! That’s right, the Longhorns’ odds to win the national championship are in an interesting situation after beating rival Oklahoma. It shook things up with the Sooners 

If Arch Manning keeps improving and limits the turnovers, the sky’s the limit again! Steve Sarkisian and crew can turn this thing around in a hurry.

Notre Dame (+1,700)

Marcus Freeman and the Irish practically erased those two losses earlier this year with four straight wins. They’re firmly in the national championship conversation.

However, they can’t afford a slip up. A 9-3 team like them probably doesn’t get in. But they have a massive opportunity with USC coming to town this weekend.

Texas Tech (+2,000)

The Red Raiders keep on winning no matter who is at quarterback. Joey McGuire’s team is running through the Big 12 right now.

So, it’s time to talk about national championship odds with Texas Tech. They’re in the top 10 among the favorites, so we’d say this is legit right now!

National Championship Odds after Week 7

Ole Miss (+2,200)
LSU (+2,500)
Oklahoma (+3,000)
Missouri (+4,000)
Tennessee (+5,000)
Michigan (+8,000)
USC (+8,000)
Vanderbilt (+8,000)
Florida (+10,000)
Auburn (+10,000)

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