Michigan vs. USC odds: Picking the Week 4 Big Ten football games

anthonytbroome

Michigan Wolverines football quarterback Alex Orji will start against USC. (Photo by Rick Osentoski-USA TODAY Sports)

The Michigan Wolverines and USC Trojans meet on Saturday in Ann Arbor to open the Big Ten season explosively. The two schools are no stranger to playing with a historic series mostly centered around the Rose Bowl, but this will be USC's first campus visit to Ann Arbor since 1958, and there's a ton of excitement for it.