Key storylines Notre Dame vs. Louisville: Holding the Cards, road warriors, Sam Hartman matters

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QBs (15) — Louisville quarterback Jack Plummer and Notre Dame quarterback Sam Hartman. (Left: Photo by Rob Kinnan-USA TODAY Sports; Right: Photo by Jim Dedmon-USA TODAY Sports)

No rest for the weary as No. 10 Notre Dame (5-1) heads to No. 25 Louisville (5-0) Saturday night for a second straight road game and the third of four consecutive prime-time matchups for the Irish.