Most of what I would say would be hard to sum up in a few word phrase.
1. Be determined to do everything that you can academically and get all that you can from your college experience. I tried to do too much, but got to do everything from learn how to operate on lab animals in the basement of the Moore Building to how to handle radioactive materials at the on-campus reactor. I had the good fortune to graduate with honors in two very different fields. Something, I was told, had only been done a couple times before. I had to take on some extra credits and my 4.33 years were a bit of a sprint, but man did I learn a ton!
I had a roommate who did the very minimum and now regrets it a lot. It's important to party a little and try out some new things (within reason) now and again. But fat, drunk and stupid is no way to take on life or school.
2. Don't commit to one girl (or guy) right away. Look at PSU as a massive smorgasbord of female delights and sample as many as you can (with their consent!). I had two buddies who met girls our freshman year and they were led around by them for the next three! Now they're both divorced, and regret that opportunity is gone by about 43 years. Meanwhile, there are a few times per month when my wife wonders what I'm sitting there smiling about.
3. Realize right now that some of the relationships you're building can last your lifetime. My roommates (well, most of them) are still my best friends 43 years later.
4. Use your physical ed credit requirements to learn some things like fly fishing, archery, and ballroom dancing (The Barrs!) that will serve you long into the future.
5. When the books are kicking your azz and the pressure feels like there's something sitting on you, take your fly rod and hike down to Spring Creek. Nothing like ripping a couple of lips to ground you and help you get back on the right track.