College Football odds: Point spreads released for every Week 6 game

Las Vegas oddsmakers have released the point spreads and odds for Week 6 games across college football. The matchups on deck promise more drama and change as the season hits the midway point.

The schedule for Week 6 features top-25 battles between Kansas and TCU, Tennessee and LSU, as well as Utah versus UCLA.

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Although the Texas A&M Aggies are no longer ranked, many eyes will be on their road game versus the No. 1 Alabama Crimson Tide after the rift between Nick Saban and Jimbo Fisher in the offseason. The Aggies’ loss to Mississippi State has dramatically moved the spread for the game from -16 Bama at the open to -25.

Check out the full slate of odds for games in Week 6.

College Football Week 6 odds, per Vegas Insider:

Wednesday, Oct. 5
SMU at UCF (-3.5)

Friday, Oct. 7
Nebraska at Rutgers (+1.5)
Houston at Memphis (-3.5)
Colorado State at Nevada (-3)
UNLV at San Jose State (-5)

Saturday, Oct. 8
Buffalo at Bowling Green (-1.5)
Purdue at Maryland (-4)
Eastern Michigan at Western Michigan (-4)
Missouri at Florida (-9.5)
Texas vs Oklahoma (+4.5)
Michigan at Indiana (+22.5)
TCU at Kansas (+4.5)
Louisville at Virginia (+5)
Tennessee at LSU (+3)
Arkansas at Mississippi State (-6)
Akron at Ohio (-12)
Georgia Southern at Georgia State (-2.5)
USF at Cincinnati (-27.5)
Kent State at Miami (OH) (+3)
Wisconsin at Northwestern (+10)
Middle Tennessee at UAB (-10)
Utah at UCLA (+3)
ECU at Tulane (-3)
Tulsa at Navy (+5.5)
Liberty at UMass (+26.5)
Ball State at Central Michigan (-8)
Toledo at Northern Illinois (+5.5)
Virginia Tech at Pitt (-14.5)
Texas Tech at Oklahoma State (-10.5)
Auburn at Georgia (-27.5)
Duke at Georgia Tech (+3)
Ohio State at Michigan State (+25)
Washington at Arizona State (+13)
Ole Miss at Vanderbilt (+18)
North Carolina at Miami (-3)
Western Kentucky at UTSA (-5)
Air Force at Utah State (+9)
Southern Miss at Troy (-6.5)
UTEP at Louisiana Tech (-1.5)
James Madison at Arkansas State (+10.5)
Wyoming at New Mexico (+3)
UConn at FIU (+4.5)
App State at Texas State (+19)
South Carolina at Kentucky (-10.5)
Notre Dame at BYU (-3)
Clemson at Boston College (+20.5)
Kansas State at Iowa State (+2)
Iowa at Illinois (-3.5)
Army at Wake Forest (-15.5)
Washington State at USC (-11)
Oregon at Arizona (+10.5)
Coastal Carolina at ULM (+15)
Texas A&M at Alabama (-25)
Florida State at NC State (-3)
Fresno State at Boise State (-7)
Hawaii at San Diego State (-20.5)
Oregon State at Stanford (+6.5)

Odds last updated on Oct. 2, 2022.