College football Week 10: Point spreads for every game

It’s hard to believe we’re coming up on the final month of the college football season, with November and Week 10 right around the corner. The first College Football Playoff ranking is set to be announced this week, meaning we’re that much closer to conference championship and bowl season.

Last week saw one big contender fall as Oklahoma dropped its first game of the season against Kansas. With plenty more big games on top this week, FanDuel has released the point spreads for the upcoming slate of action.

Fans will get to take in some big rivalry games such as LSU-Alabama and Oklahoma-Oklahoma State, as well as a big top 25 matchup in the SEC between Georgia and Missouri. You can view the point spreads for those games and every other Week 19 college football contest below.

No. 25 Kansas State at No. 7 Texas (-6.5)

Details: noon ET on Saturday, Nov. 4 on FOX
Texas had no problem against BYU despite playing without quarterback Quinn Ewers on its way to a 35-6 win on Saturday. Maalik Murphy filled in as the starter to throw for 170 yards, two touchdowns and an interception as the Longhorns defense stepped up to force three turnovers.

The Longhorns will still be without Ewers this week as they face a Kansas State team that has come to life over the past few weeks. Playing a two quarterback system with both Will Howard and Avery Johnson, the Wildcats have outscored their opponents 81-3 over the past two weeks. They’ll aim to keep that up as the competition gets stiffer in Austin.

No. 12 Notre Dame (-3) at Clemson

Details: Noon ET on Saturday, Nov. 4 on ABC
Things haven’t gone the way either of these teams would have hoped this season. It’s looking especially bad for Clemson, which is now 4-4 on the season and near the bottom of the ACC standings, an unfamiliar position during the coaching tenure of Dabo Swinney.

Notre Dame has a respectable 7-2 record but the way it lost those two games stings as there is little hope of making the College Football Playoff. The Fighting Irish are coming off of back-to-back wins and will now hope to continue to salvage what’s left of the year and finish strong.

Texas A&M at No. 11 Ole Miss (-4.5)

Details: Noon ET on Saturday, Nov. 4 on ESPN
Ole Miss hasn’t lost since dropping its SEC opener to Alabama and will aim to keep itself alive in the SEC West race by making it five straight on Saturday. The Rebels run into a Texas A&M team that recently got back on track with a 30-17 win against South Carolina and try to carry that momentum into this game.

The Aggies have one of the best defensive fronts in the conference and are one of only two teams in the SEC holding teams under 100 yards rushing per game. It will be interesting to see how Ole Miss attacks that on offense with Quinshon Judkins as well as quarterback Jaxson Dart and his ability to make plays with his legs.

Arkansas at Florida (-6.5)

Details: Noon ET on Saturday, Nov. 4 on ESPN
Florida appeared to be gaining some steam heading into a matchup with Georgia this past weekend, but ultimately fell 43-20 to the Bulldogs. Now the Gators have a good opportunity to get back on track at home against an Arkansas team that has been abysmal so far.

The Razorbacks are one of just two teams still searching for their first SEC win, having dropped six games in a row. Three of those six losses have come by a touchdown or less, so they’re still managing to stay competitive, but this seems like a game Florida should have little trouble winning.

No. 14 Missouri at No. 1 Georgia (-17)

Details: 3:30 p.m. ET on Saturday, Nov. 4 on CBS
Missouri has been one of the surprise teams in the SEC this season, earning their way into a 7-1 record, the most wins since Eli Drinkwitz took over in 2020. However, the Tigers will be truly put to the test this week against defending national champion and No. 1 Georgia.

The Bulldogs are on a program record 20-game win streak and can take a big step toward once against claiming the SEC East with a win here. Star tight end Brock Bowers is out with injury, but Georgia still looked fairly dominant in a 43-20 win against Florida this past week.

No. 10 Oklahoma (-6.5) at Oklahoma State

Details: 3:30 p.m. ET on Saturday, Nov. 4 on ABC
Saturday will mark the final Bedlam game for the foreseeable future as Oklahoma prepares to join the SEC next season. The rivalry is one of the oldest in college football, having been played on an annual basis since 1910.

The Sooners have a major advantage historically, holding a 91-19-7 all-time advantage. However, they recently dropped their first game of the season this past week 38-33 against Kansas. Meanwhile, the Cowboys are on a four-game winning streak and have the homefield advantage in this one, so don’t expect them to go down easily.

No. 5 Washington (-3) at No. 24 USC

Details: 7:30 p.m. ET on Saturday, Nov. 4 on ABC
The only unbeaten remaining in the Pac-12, Washington is the favorite to represent the conference in the College Football Playoff entering Week 10. Michael Penix Jr. has made a strong case for the Heisman to this point, leading the country with 2,945 yards passing, 24 touchdowns and six interceptions.

Caleb Williams, last year’s Heisman winner, is right behind him to rank second 2,646 yards, 25 touchdowns and four interceptions. The Trojans barely escaped a lackluster Cal team 50-49 this past week and it would seem their defense is severely outmatched against the nation’s top passing attack.

Kentucky (-3.5) at Mississippi State

Details: 7:30 p.m. ET on Saturday, Nov. 4 on SEC Network
Kentucky enters this game having lost three straight, but this seems like a good spot for the Wildcats to potentially get back on track. Mississippi State’s lone SEC win comes against Arkansas, and it has been the worst scoring offense in the conference with just 25.1 points per game.

That said, this is a road game for the Wildcats so that could play a factor. They’ll need to be more effective in the running game after managing just 72 yards on the ground in their most recent loss to Tennessee.

No. 13 LSU at No. 8 Alabama (-3.5)

Details: 7:45 p.m. ET on Saturday, Nov. 4 on CBS
Last year’s game between Alabama and LSU came down to overtime as Jayden Daniels completed a two-point conversion to escape with a 32-31 win. The Tigers went on to win the SEC West, and still have a chance to do so this year if they can beat the Crimson Tide again.

Alabama is currently the favorite to claim the division title thanks to an unblemished 5-0 conference record, and this game seems like its biggest test left. LSU boasts the top scoring offense in the SEC, while the Crimson Tide are the top scoring defense, setting up for what should be a tight battle.

No. 16 Oregon State (-13.5) at Colorado

Details: 10 p.m. ET on Saturday, Nov. 4 on ESPN
Colorado has now lost four of its past five games after beginning the season with a 3-0 record. The Buffaloes offense struggled this past week in a 28-16 loss to UCLA, and things won’t get any easier against an Oregon State defense that ranks fourth in the Pac-12 against the pass.

Still, Colorado has two of the most explosive players in the country in Shedeur Sanders and Travis Hunter. It has also played slightly better at home this season, so there is some hope it can at least keep things close and make for an entertaining game.

Point spreads for every other Week 10 college football game

Tuesday, Oct. 31
Northern Illinois (-3.5) at Central Michigan
Buffalo at Toledo (-14.5)

Wednesday, Nov. 1
Ball State at Bowling Green (-6.5)
Kent State at Akron (-3.5)

Thursday, Nov. 2
TCU at Texas Tech (-2.5)
Wake Forest at Duke (-12.5)
South Alabama at Troy (-6.5)

Friday, Nov. 3
Boston College at Syracuse (-3)
Colorado State at Wyoming (-7.5)

Saturday, Nov. 4
No. 3 Ohio State at Rutgers
UConn at No. 19 Tennessee (-34.5)
Wisconsin (-8.5) at Indiana
Nebraska (-3.5) at Michigan State
Jacksonville State at South Carolina (-14.5)
Campbell at North Carolina
Kennesaw State at Sam Houston State
Arizona State at No. 18 Utah (-10.5)
Georgia Tech at Virginia (-2.5)
Navy (-7) at Temple
Army at No. 17 Air Force (-18.5)
Florida Atlantic at UAB
UTSA at North Texas
South Florida at Memphis
Louisiana at Arkansas State
No. 4 Florida State (-21.5) at Pittsburgh
No. 9 Penn State (-11.5) at Maryland
Virginia Tech at No. 15 Louisville (-9.5)
No. 21 Tulane at East Carolina
No. 23 James Madison at Georgia State
Illinois at Minnesota (-3)
Iowa (-5.5) at Northwestern
Merrimack at Massachusetts
Houston at Baylor (-4.5)
UCF (-4.5) at Cincinnati
Coastal Carolina at Old Dominion
Auburn (-13.5) at Vanderbilt
Charlotte at Tulsa
Louisiana-Monroe at Southern Miss
Hawaii at Nevada
California at No. 6 Oregon (-23.5)
Louisiana Tech at Liberty
Middle Tennessee at New Mexico State
Marshall at Appalachian State
UNLV at New Mexico
No. 22 Kansas (-1.5) at Iowa State
BYU at West Virginia (-8)
Georgia Southern at Texas State
Utah State at San Diego State
Purdue at No. 2 Michigan (-31.5)
SMU at Rice
Miami (-4.5) at NC State
Western Kentucky at UTEP
Stanford at Washington State (-13.5)
Boise State at Fresno State (-3.5)
No. 20 UCLA (-1.5) at Arizona