College football Week 12: Point spreads for every game

College football season is approaching its end, with Week 12 set to mark the second-to-last week of the regular season. There’s plenty of exciting games on tap as bowl season approaches, and FanDuel has released the point spreads for some of the top matchups.

Last week saw some big-time games between top 25 opponents, with Georgia handing Ole Miss a 52-17 drubbing and Washington keeping its undefeated season alive with a 35-28 win against Utah. This week features several more exciting games, some of which have conference title implications on the line.

Louisville can reach the ACC Championship Game with a win, while Washington also has another tough matchup against a ranked Oregon State team. You can view the full point spreads for ever Week 12 college football game below.

No. 3 Michigan (-20.5) at Maryland

Details: Noon ET on Saturday, Nov. 18 on FOX
Jim Harbaugh missed Saturday’s game against Penn State as he serves a suspension to close out the regular season, but the Wolverines still earned a critical 24-15 victory. With sign-stealing allegations hanging over its head, some of the focus has been taken away from just how good Michigan has been this season.

The Wolverines are No. 1 in the country in total defense and scoring defense and boast a strong rushing attack with Blake Corum, who had 145 yards and two touchdowns against the Nittany Lions. Ohio State is looming next week, but Michigan has an interesting test here against a Maryland passing attack that ranks second in the Big Ten.

No. 11 Louisville (-2.5) at Miami

Details: Noon ET on Saturday, Nov. 18 on ABC
Louisville can clinch a spot in the ACC Championship with a win here, which would be quite the feat in coach Jeff Brohm‘s first season. The Cardinals went from 8-5 last year to now being 9-1 with two games remaining and being ranked among the top 12 in the College Football Playoff.

Louisville has gotten to this point on the back of one of the ACC’s top defenses as well as running back Jawhar Jordan, who is nearing 1,000 yards on the season. This is a game they should win against a Miami team that has dropped four of its past six, but the Cardinals must overcome a tough road environment to do so.

No. 2 Georgia (-10) at No. 13 Tennessee

Details: 3:30 p.m. on Saturday, Nov. 18 on CBS
Tight end Brock Bowers made his return from injury after missing the past two games, and Georgia responded with a 52-17 rout of Ole Miss. The Bulldogs have now won 27 straight contests, clinched their spot in the SEC Championship Game and are on their quest to win a third straight national championship.

They appear to be peaking at the right time with two games remaining in the regular season and run into a Tennessee team coming off of a 36-7 loss to Missouri. The Vols haven’t won against Georgia since 2016, and with the way the Bulldogs looked last week face a tall task in breaking that streak this year.

UCLA at USC (-5.5)

Details: 3:30 p.m. ET on Saturday, Nov. 18 on ABC
Things continued to trend downward for the Trojans, who have now lost four of their past five games. They fired defensive coordinator Alex Grinch after last week’s loss to Washington, but didn’t look much better Saturday in a 36-27 loss to Oregon.

Bo Nix torched the USC secondary for 412 yards passing and four total touchdowns as the Ducks held a 29-14 lead after three quarters. The Pac-12 titles hopes are gone, but the Trojans still have a chance to close the season strong against a UCLA team that has also lost back-to-back games.

No. 24 North Carolina at Clemson (-7)

Details: 3:30 p.m. ET on Saturday, Nov. 18 on ESPN
North Carolina still has an outside shot to make the ACC title game, but would need to win here as well as for Louisville to lose. The Tar Heels started off this season 6-0 before suffering a pair of losses, but have since got back on track and most recently beat Duke 47-45 in Week 11.

Clemson also appears to be coming together after what has been a disappointing season so far. The Tigers are coming off of a 42-21 win against Georgia Tech in which the defense forced four interceptions and Cade Klubnik through for four touchdowns, so will hope to keep that momentum going here at home.

No. 25 Kansas State (-7.5) at No. 16 Kansas

Details: 7 p.m. ET on Saturday, Nov. 18 on FS1
It’s not often that both schools are ranked entering the Sunflower Showdown, but for now that will be the case when the Wildcats travel to Lawrence. Kansas has lost 14 straight games to K-State, but has played a lot better in recent years and its seven wins this year are already the most since 2008, the last year it won this game.

However, the Jayhawks face some injury concerns entering this game after quarterback Jason Bean left Saturday’s loss to Texas Tech. That forced them to have to turn to third-string QB Cole Ballard, and they could have to lean more on their run game if Bean is out for this one.

No. 5 Washington (-1.5) at No. 12 Oregon State

Details: 7:30 p.m. ET on Saturday, Nov. 18 on ABC
Michael Penix Jr. continued to look good Saturday against a solid Utah defense, throwing for 332 yards and three touchdowns while rushing for another. The Huskies managed to escape with a 35-28 win to improve to 10-0 as their quest for a Pac-12 title and College Football Playoff berth continues.

They’ll face another test here against an Oregon State team fighting for its chance to reach the conference title game. The Beavers close the season against rival Oregon, and if they somehow manage to pull off an upset here would enter that week with an opportunity to finish above the Ducks in the standings.

Florida at No. 14 Missouri (-11.5)

Details: 7:30 p.m. ET on Saturday, Nov. 18 on ESPN
Missouri showed little hangover after a tough loss to Georgia this past week, bouncing back to hand Tennessee a 36-7 loss. Cody Shrader, the SEC’s leading rusher, had another impressive performance to finish the game with 205 yards rushing and a touchdown as well as five catches for a team-high 116 yards.

The Tigers have already achieved the most wins since Eli Drinkwitz took over in 2020, and have a realistic chance to reach the 10-win mark with two games remaining. Florida has now lost three in a row, and Mizzzou next faces an Arkansas team near the bottom of the league standings to close the season.

No. 7 Texas (-8.5) at Iowa State

Details: 8 p.m. ET on Saturday, Nov. 18 on FOX
Quarterback Quinn Ewers made his return this past week for Texas after missing the past two games with a shoulder injury. The Longhorns narrowly escaped TCU with a 29-26 victory, marking the second straight week they won by a three-point margin.

Ewers finished the game 22-of-33 passing for 317 yards, one touchdowns and one interception. He’ll look to continue to shake off the rust against Iowa State as Texas fights to secure its spot in the Big 12 Championship, currently sitting atop the conference standings with a 6-1 league record.

No. 18 Utah (-1.5) at No. 21 Arizona

Details: Saturday, Nov. 18 — time/TV TBA
Utah missed a big opportunity this past week against No. 5 Washington, taking the Huskies down to the wire before falling 35-28. They’re now out of the running to compete for a Pac-12 Championship after winning the conference in 2021 and 2022, but this game should still have plenty of intrigue.

Arizona enters as one of the hottest teams in the conference, having won four straight games and currently tied for third in the league standings. The Wildcats are coming off of a 34-31 victory against Colorado and will aim to continue climbing up the rankings here.

Point spreads for every other Week 12 college football game

Tuesday, Nov. 14
Toledo (-10.5) at Bowling Green
Western Michigan at Northern Illinois (-3.5)
Akron at Eastern Michigan (-5.5)

Wednesday, Nov. 15
Central Michigan at Ohio (-7.5)
Buffalo at Miami (OH) (-8.5)

Thursday, Nov. 16
Boston College (-1.5) at Pittsburgh

Friday, Nov. 17
South Florida at UTSA (-16.5)
Colorado at Washington State (-4.5)

Saturday, Nov. 18
No. 6 Oregon at Arizona State
Chattanooga at No. 8 Alabama
UL-Monroe at No. 9 Ole Miss (-35.5)
Rutgers at No. 10 Penn State
No. 17 Oklahoma (-24.5) at BYU
No. 23 Tulane (-9.5) at Florida Atlantic
Coastal Carolina (-5.5) at Army
Michigan State at Indiana (-5.5)
Southern Miss at Mississippi State (-13.5)
Purdue at Northwestern (-1.5)
Abilene Christian at Texas A&M
Sacred Heart at UConn
East Carolina at Navy (-2.5)
SMU (-7.5) at Memphis
Massachusetts at Liberty
Louisiana Tech at Jacksonville State
UTEP at Middle Tennessee
Rice at Charlotte
Appalachian State at James Madison
Kent State at Ball State
Hawaii at Wyoming
Cincinnati at West Virginia
Duke at Virginia
North Texas at Tulsa
Temple at UAB
Texas State at Arkansas State
Nevada at Colorado State
Wake Forest at No. 20 Notre Dame (-24.5)
Illinois at No. 22 Iowa (-4.5)
Sam Houston at Western Kentucky
NC State at Virginia Tech
Baylor at TCU
Louisiana at Troy
UNLV at Air Force
Minnesota at No. 1 Ohio State
No. 15 Oklahoma State at Houston
New Mexico State at Auburn
UCF at Texas Tech
Marshall at South Alabama
Old Dominion at Georgia Southern
North Alabama at No. 4 Florida State
California at Stanford
Boise State at Utah State
Florida International at Arkansas
Kentucky (-2.5) at South Carolina
Nebraska at Wisconsin
Georgia State at No. 19 LSU
Syracuse at Georgia Tech
New Mexico at Fresno State
San Diego State at San Jose State