Honestly, don't think I'd change much in regard to Penn State.
I was always gonna go to Penn State, but there is a part of me that I wished I went to a city school those years. I grew up outside Linglestown, which is outside of Harrisburg. I've never really lived in a city.
Hmmmm...you and I may have walked similar hallways albeit 10-15 years apart. I grew up there and always felt like it was the perfect suburban atmosphere, so much so that I never considered PSU because outside of football season, it was gonna be a bit of a drag. Having older friends that were already there and them telling me about some experiences helped cement my opinion. So I went just far enough away in a more metropolitan area that was also close enough that I could take advantage of my parents having PSU season tickets.
As for the original question of the post, I'd say that I wish I had taken more chances socially instead of always playing the cautious introvert card. I look at my big picture now and I couldn't ask for much better on the professional side but the personal side has always been lacking and I feel like the foundation of both of those were built by my college experience. C'est la vie, I guess.