I come from a long line of high BP and cholesterol. My Dr started me on Lipitor, liver enzyme levels shot up right away and I ached all over. Then we did Baycol, same thing. Then we went the more natural way which was what I had hoped for with Niaspan (niacin and vitamin B3 mixture), that worked bringing the level down pretty good but one of the common side effects is "flushing". This is from their website "Niaspan ER can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin)" They said take it at bedtime because hopefully you sleep through the "flushing" Not me, I would wake up every morning about 2:00 a.m. and feel like I had been severely sunburned on my back and stomach on the beach that day. I was hot, itchy, red, and the sheets hurt my skin even. Couldn't keep that up so we tried generic Crestor (Rosuvastatin) and its been great, bad cholesterol down, good cholesterol up just like it should be and hasn't been this good since my 30's (60 now) I've been on it for about 11 years. I've got some joint aches but I've also come from a long line of arthritic people so I guess its better to have good statin levels and some arthritis than bad levels of statins if they are causing any of the aches.